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ГЕРОНТОЛОГИЯ
«GERONTOLOGY» Scientific Journal

КЛИНИЧЕСКАЯ ГЕРОНТОЛОГИЯ

COGNITIVE IMPAIRMENTS AND THEIR PROGNOSIS IN PATIENTS WITH CORONARY ARTERY DISEASE OF DIFFERENT AGE GROUPS WHO UNDERWENT ON-PUMP CABG

Shevtsov R.Yu.1, Lykov Yu.A.1
1. The National Research University « Belgorod State University» (BelSU), Belgorod, Russia
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Summary:
Purpose of the research: To analyze the scientific literature on this topic published in the electronic databases SCOPUS, PubMed and Scholar over the past 10 years. Coronary artery bypass grafting (CABG) is one of the most common heart surgeries. It improves the quality of life of patients with clinically significant angina pectoris, increases life expectancy, and has a low risk of intra- and postoperative complications. About 300 thousand CABG operations are performed worldwide every year. CABG is the most effective and common method of surgical treatment of coronary artery disease (CAD) and is considered the gold standard for the treatment of multivessel coronary artery disease. However, the problem of damage to the nervous system during cardiac surgery is still relevant, despite the improvement of surgical methods. Cognitive impairment remains one of the most common complications of CABG. At present, cognitive impairments that have arisen in the postoperative period are combined with the term "postoperative cognitive dysfunction" (POCD), which develops in the early and persists in the late postoperative period. POCD is a recognized clinical phenomenon that has a multifactorial origin and occurs after any surgical operations, including cardiac surgery, its frequency can range from 5 to 86%.
Keywords postoperative cognitive dysfunction (POCD), coronary artery bypass grafting, cerebral ischemia, S100B, cerebral enolase, cognitive reserve, cholinergic activity, neuroinflammation, neuropsychological testing, parecoxib.

Bibliographic reference:
Shevtsov R.Yu., Lykov Yu.A., COGNITIVE IMPAIRMENTS AND THEIR PROGNOSIS IN PATIENTS WITH CORONARY ARTERY DISEASE OF DIFFERENT AGE GROUPS WHO UNDERWENT ON-PUMP CABG // «GERONTOLOGY» Scientific Journal. - 2020. - №3;
URL: http://www.gerontology.su/magazines?textEn=310 (date of access: 19.04.2024).

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