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«GERONTOLOGY» Scientific Journal

RON DEFICIENCY ANEMIA IN OLD AGE AS A FACTOR AGGRAVATING THE CLINICAL COURSE OF CORONARY HEART DISEASE

Chizhova M.A.1, Hammad E.V.1,2, Mursalov U.S.3, Pozdnyakova N.M.1
1. «Gerontology» Research Medical Center, Moscow, Russia
2. Federal state Autonomous institution "Medical and rehabilitation center" Ministry of health of the Russian Federation, Moscow, Russia
3. St. Petersburg Institute of bioregulation and gerontology, St. Petersburg, Russia
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Summary:
Coronary heart disease is often accompanied by iron deficiency anemia, the frequency of which ranges from 10 to 79% depending on the age and sex of patients, severity of clinical manifestations and criteria for diagnosis of anemia. However, anemic syndrome in coronary heart disease not reflected properly as a problem in any national guidance. If the role of heavy degrees of anemia can be assumed, the forecast and impact of mild anemia on the course of coronary heart disease and its forms are not clear in elderly patients. In the article the problem is illuminated by the impact of iron deficiency anemia on the course of coronary heart disease in the elderly. It is established that iron deficiency anemia contributes to decreased antioxidant defense mechanisms in the elderly and activation procyclically processes in a significantly higher degree than middle aged people. It was found that the presence of iron deficiency anemia worsens the course of ischemic heart disease, which is manifested in the form of increased neuroimmunoendocrine imbalance. The presence of iron deficiency anemia even mild is a significant risk factor for an unfavorable course of coronary heart disease in the elderly along with such traditional factors as arterial hypertension, hypercholesterolemia and other.
Keywords coronary heart disease, anemia, elder

Bibliographic reference:
Chizhova M.A., Hammad E.V., Mursalov U.S., Pozdnyakova N.M., RON DEFICIENCY ANEMIA IN OLD AGE AS A FACTOR AGGRAVATING THE CLINICAL COURSE OF CORONARY HEART DISEASE // «GERONTOLOGY» Scientific Journal. - 2016. - №2;
URL: http://www.gerontology.su/magazines?textEn=250 (date of access: 18.08.2018).

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