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«GERONTOLOGY» Scientific Journal

BIOMARKERS OF AGING: FROM FUNCTION TO MOLECULAR BIOLOGY

Hammad E.V.1
1. Federal Government Autonomic Organization "Medical rehabilitation center" of Russian Federation, Moscow, Russia
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Summary:
In this article it is shown that the group of people the same age there are different indicators of disease risk and functional disorders. This observation confirms the necessity of finding reliable biomarkers that will allow us to accurately characterize the complex mechanism of aging. The search of biomarkers is complicated by the biological peculiarities of each individual organism, an individual lifestyle, as well as taking various drugs. Thus, there is no single biomarker or "gold standard" for monitoring the success or the physiological process of aging. In this article the modern data about potential aging biomarkers and their role in physiological processes (physical activity, digestion, the function of the endocrine and immune systems, and others) that are violated in the course of aging. Special attention is paid to molecular biomarkers: mi RNA, bilirubin, end products of glycation and others.
Keywords biomarkers, aging, molecular biomarkers, biomarkers of aging, interleukins, cytokine status, molecular interaction, oxidative stress, glycation, telomere, RNA, molecular biology.

Bibliographic reference:
Hammad E.V., BIOMARKERS OF AGING: FROM FUNCTION TO MOLECULAR BIOLOGY // «GERONTOLOGY» Scientific Journal. - 2017. - №1;
URL: http://www.gerontology.su/magazines?textEn=229 (date of access: 24.11.2017).

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