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«GERONTOLOGY» Scientific Journal

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PECULIARITIES OF TARGET ORGANS CHANGES AND LIPID STATUS OF ELDERLY PATIENTS WITH UNCOMPLICATED ARTERIAL HYPERTENSION ON THE BACKGROUND OF NON-SPECIFIC ENDOGENOUS INFLAMMATION

Ukraintseva D.N.1, Gorshunova N.K.1
1. Kursk state medical University of the Ministry of health of Russia, Kursk, Russia
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Summary:
In the order to study the features of the lesion of common carotid artery (CCA), the left ventricle, the lipid status 74 elderly patients suffering from a not complicated AH with varying degrees of nonspecific endogenous inflammation and 30 practically healthy older persons were examined. Different levels of nonspecific endogenous inflammation that is not dependent on the availability of hemodynamic overload and parameters of the blood lipid spectrum were revealed. Increase of the of C-reactive protein (CRP) level in subclinical range in elderly patients with hypertension accompanied by a reduction of the low-density lipoprotein (LDL) resistance to oxidation. CRP level was an independent factor associated with the reduction of oxidative resistance of atherogenic lipoproteins. Increase of intensity of nonspecific endogenous inflammation accompanied by a thickening of the complex intima-media of a CCA without statistically significant changes in the prevalence of atherosclerotic lesions of the vessel and morphological parameters of myocardium.
Keywords arterial hypertension, intima-media thickness of the common carotid artery, resistance of LDL to oxidation, C-reactive protein, old age.

Bibliographic reference:
Ukraintseva D.N., Gorshunova N.K., PECULIARITIES OF TARGET ORGANS CHANGES AND LIPID STATUS OF ELDERLY PATIENTS WITH UNCOMPLICATED ARTERIAL HYPERTENSION ON THE BACKGROUND OF NON-SPECIFIC ENDOGENOUS INFLAMMATION // «GERONTOLOGY» Scientific Journal. - 2014. - №1;
URL: http://www.gerontology.su/magazines?textEn=148 (date of access: 24.11.2017).

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